Creatinine clearance (CrCl) is the volume of blood plasma cleared of creatinine per unit time.

Estimate using the Cockcroft-Gault equation: <h3 class="ql-align-center">﻿<math xmlns="http://www.w3.org/1998/Math/MathML"><semantics><mrow><mi>C</mi><mi>l</mi><mi>C</mi><mi>r</mi><mo stretchy="false">(</mo><mi>m</mi><mi>L</mi><mi mathvariant="normal">/</mi><mi>m</mi><mi>i</mi><mi>n</mi><mo stretchy="false">)</mo><mo>=</mo><mfrac><mrow><mn>1.2</mn><mo>×</mo><mo stretchy="false">(</mo><mn>140</mn><mtext>–</mtext><mi>a</mi><mi>g</mi><mi>e</mi><mo stretchy="false">)</mo><mo>×</mo><mi>w</mi><mi>e</mi><mi>i</mi><mi>g</mi><mi>h</mi><mi>t</mi><mo stretchy="false">(</mo><mi>k</mi><mi>g</mi><mo stretchy="false">)</mo></mrow><mrow><mi>s</mi><mi>e</mi><mi>r</mi><mi>u</mi><mi>m</mi><mi>C</mi><mi>r</mi><mi>e</mi><mi>a</mi><mi>t</mi><mi>i</mi><mi>n</mi><mi>i</mi><mi>n</mi><mi>e</mi><mo stretchy="false">(</mo><mi>μ</mi><mi>m</mi><mi>o</mi><mi>l</mi><mi mathvariant="normal">/</mi><mi>L</mi><mo stretchy="false">)</mo></mrow></mfrac></mrow><annotation encoding="application/x-tex">ClCr (mL/min) = \frac{1.2 \times(140 – age)\times weight(kg)}{serumCreatinine (\mu mol/L)}</annotation></semantics></math>ClCr(mL/min)=serumCreatinine(μmol/L)1.2×(140–age)×weight(kg)​﻿</h3>

Creatinine Clearance (ClCr)